Cells adapt to aging by actively remodeling endoplasmic reticulum, study reveals

Published on February 2, 2026

Phys.org
Phys.org

Quick Summary

Positive Story
Who Kris Burkewitz and team
What Discovered cells remodel the endoplasmic reticulum (ER) during aging via ER-phagy
Where In Caenorhabditis elegans worms (model organism)
When Published in Nature Cell Biology, research ongoing
Impact This discovery could lead to new treatments for age-related diseases, promoting healthy aging.
Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of life, but it is associated with a greatly increased incidence of most chronic diseases, including various cancers, diabetes, and Alzheimer's disease.

Related

People Kris Burkewitz Eric Donahue
Organizations Burkewitz lab Vanderbilt University
Topics Aging Endoplasmic Reticulum ER-phagy Cellular Biology

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